The Occurrence of 275 Rare Diseases and 47 Rare Disease Groups in Italy. Results from the National Registry of Rare Diseases.

Int J Environ Res Public Health · 2018 · PMC6068991 · PMID 30002291

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an increasing trendno p-value reported

The time course of CD notifications showed an increasing trend from 2006 to 2013, when the median of notifications attained the maximum value.

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