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A randomized, controlled trial comparing the metformin, oral contraceptive pills and their combination in patients with polycystic ovarian syndrome.

J Family Med Prim Care · 2018 · PMC6069641 · PMID 30112307

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a definite trendno p-value reported
The use of metformin has resulted in a definite trend toward changing the metabolic milieu of the patient.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.