almost significantp = 0.056
In the men currently treated with agalsidase, the correlation between lysoGb3 plasma levels and RRA was almost significant (Spearman’s test, r = − 0.34, p = 0.056, n = 33); the trend remained when focused on the classic phenotype alone (Spearman’s test, r = − 0.43, p = 0.055, n = 21) but not when focused on the non-classic phenotype (Spearman’s test, r = − 0.004, p = 0.99, n = 12).