Barely Significant
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Exposure to amitraz, fipronil and permethrin affects cell viability and ABC transporter gene expression in an Ixodes ricinus cell line.

Parasit Vectors · 2018 · PMC6069974 · PMID 30064465

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highly significantno p-value reported
The ABCB1 gene showed dose-dependent downregulation, which was highly significant at 150 μM with all three drugs.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.