Defining the hydrophobic interactions that drive competence stimulating peptide (CSP)-ComD binding in <i>Streptococcus pneumoniae</i>.

Beilstein J Org Chem · 2018 · PMC6071684 · PMID 30112082

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closest p

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an interesting trendno p-value reported

The eighth position exhibited an interesting trend where truncation of the side-chain (Phe → Phg) was not tolerated (>80-fold reduction in potency) while elongation of the chain (Phe → hPhe) resulted in only a modest reduction in potency (4-fold change; Table 1 ).

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