N‑terminal truncated peroxisome proliferator‑activated receptor‑γ coactivator‑1α alleviates phenylephrine‑induced mitochondrial dysfunction and decreases lipid droplet accumulation in neonatal rat cardiomyocytes.

Mol Med Rep · 2018 · PMC6072228 · PMID 29901150

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In addition, NT-PGC-1α-overexpressing NRCMs exposed to 10 μM PE or 500 nM MK886 displayed an increasing trend in oxygen consumption, that was slower compared with NT-PGC-1α-overexpressing NRCMs that had not been exposed to PE or MK886.

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