An Insight into the Difficulties in the Discovery of Specific Biomarkers of Limbal Stem Cells.

Int J Mol Sci · 2018 · PMC6073450 · PMID 29986467

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a decreasing trendno p-value reported

It has been reported that knockout of Abcb5 genes in mice induced a decreasing trend of LSC, which accounted for the depletion of quiescent LSCs due to enhanced proliferation and pro-apoptotic p53 and downregulating antiapoptotic Bcl2 and Bcl-x , leading to defective corneal differentiation and wound healing [ 8 ]. 4.3.

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