Non-invasive assessment of liver disease in rats using multiparametric magnetic resonance imaging: a feasibility study.

2 B) with no significant difference between both timepoints. Quantification of hepatic fat by MRI [mean of three regions of interest (ROIs)] showed a highly significant increase in PDFF after both 4 and 8 weeks on an MCD diet, reaching 23.81±6.00% and 23.84±5.64% compared with control animals, where PDFF was 1.73±0.94% ( P =0.0005) and 2.09±1.16% ( P <0.0001), respectively ( Fig. 2 A,C).

also in 132,142 other papers