TMEM30A is a candidate interacting partner for the β-carboxyl-terminal fragment of amyloid-β precursor protein in endosomes.

PLoS One · 2018 · PMC6080755 · PMID 30086173

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a decreasing trendno p-value reported

Compared with the wild-type, the KKLN mutant showed a decreasing trend of FL-APP and APP-CTF accumulation.

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an increasing trendno p-value reported

The transfection of CFP-tagged or untagged TMEM30A showed an increasing trend of FL-APP and APP-CTFs ( Fig 4B ), as observed in Fig 2A .

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