In our final set of models, where excess SNP-by-SNP homozygosity ( F SNP ) was included as an additional covariate, AFS and FI remained significantly associated with F ROH after accounting for multiple testing and FEV1 was marginally significant ( Table 2 ).
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Relationships between estimated autozygosity and complex traits in the UK Biobank.
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The sentences
Similarly, in 2012 we found a small but highly significant association between schizophrenia and F ROH across 17 case-control datasets (total N = 21,844 [ 20 ]).