borderline significancep = .052
Radiotherapy (p < .0001; HR = 0.3368), chemotherapy (p = .028; HR = 0.7143) and the combination of detectable levels of serum IFN-γ/TNF-α/IL-17A correlated positively with an improved survival profile (p = .003; HR = 1.7851), with borderline significance for serum IL-4/IL-5/IL-6 (p = .052; HR = 2.2645).