Barely Significant
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The deletion of M<sub>4</sub> muscarinic receptors increases motor activity in females in the dark phase.

Brain Behav · 2018 · PMC6085911 · PMID 29978954

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highly significantp < 0.0001actually significant
Although these increases were highly significant (ANOVA: F 25,429 = 1434, p < 0.0001; F 13,95 = 13.64, p < 0.0001), they were really small (see Supporting Information Tables S4 and S5 ) in units of percent (females vs. males) both in WT and KO animals. 3.3.

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