Apparent bias toward long gene misregulation in MeCP2 syndromes disappears after controlling for baseline variations.

Finally, when we examined downregulation of long genes from the GRO-seq (global nuclear run-on with high-throughput sequencing) data collected from these mice, we confirmed a marginal significance in the downregulation of long genes, but upregulation of long genes was not observed in whole-cell RNA-seq data (Supplementary Fig. 4 ).

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