Changes in bone mineral density and bone metabolic indexes in ankylosing spondylitis mouse model complicated with osteoporosis.

Exp Ther Med · 2018 · PMC6090276 · PMID 30116335

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an increasing trendno p-value reported

OP affects approximately 9 million new cases per year worldwide, and incidence of this disease shows an increasing trend, causing serious medical and financial burden to society and family ( 13 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.