Postoperative Pain Management after Impacted Third Molar Surgery with Preoperative Oral Lamotrigine, a Randomized, Double-blind, Placebo-Controlled Trial.

Lamotrigine showed to be slightly more effective than placebo in this study with limited cases and statistical analysis achieved a hardly significant power.[ 12 ] As mentioned earlier, lamotrigine has been studied in the past for management of painful neuropathic conditions with only few establishing their efficacy in trigeminal neuralgia.

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