4 Its main drawback is the resultant skin and tissue scarring and defects that might be significant in cases of very large tumors, leading to functional and esthetic sequelae and requiring extensive reconstructive surgery. 3 , 5 Many topical and systemic treatments have been used, either alone when surgery is contraindicated and for recurrences or as adjuvants.
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Giant condyloma acuminatum of the vulva: Successful management with imiquimod.
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