In our 2004–2006 US national study of clinical HAdV infections from 22 laboratories, we found a relatively low prevalence of HAdV21 (2.1%) among 2189 typed HAdV specimens, an increased risk (odds ratio, 7.6; 95% confidence interval, 2.6–22.3) of severe disease compared with the more common HAdV3 infections, and an increasing trend of HAdV21 detections over time [ 10 ].
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Adenovirus Type 21 Outbreak Among Lung Transplant Patients at a Large Tertiary Care Hospital.
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