NPAS4 recruits CCK basket cell synapses and enhances cannabinoid-sensitive inhibition in the mouse hippocampus.

By contrast, and consistent with what has been described previously ( Bloodgood et al., 2013 ), we detected a highly significant NPAS4-dependent increase in somatic inhibitory synapses in tissue from mice housed in EE ( Figure 1E and F ; WT: 277.3 ± 14.2 AU, KO: 209.4 ± 6.8 AU, p<0.001, two-way ANOVA with Bonferroni post hoc test).

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