Interaction Between Environmental Risk Factors and Catechol-O-Methyltransferase (COMT) and X-Ray Repair Cross-Complementing Protein 1 (XRCC1) Gene Polymorphisms in Risk of Lung Cancer Among Non-Smoking Chinese Women: A Case-Control Study.

Med Sci Monit · 2018 · PMC6106617 · PMID 30109864

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a worrying trendno p-value reported

Statistics have revealed a worrying trend regarding the disease demographics, highlighting a 2-fold increase in the incidence of lung cancer over the past 30 years [ 3 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.