Linking a role of lncRNAs (long non-coding RNAs) with insulin resistance, accelerated senescence, and inflammation in patients with type 2 diabetes.

Hum Genomics · 2018 · PMC6107963 · PMID 30139387

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highly significantno p-value reported

While lncRNA PLUTO has been shown to be downregulated in islets from donors who are patients with type 2 diabetes and pre-diabetes subjects [ 33 ], our study observed a highly significant upregulation of PLUTO in patients with type 2 diabetes.

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