The <i>Nrf2</i>-Antioxidant Response Element Signaling Pathway Controls Fibrosis and Autoimmunity in Scleroderma.

Front Immunol · 2018 · PMC6109691 · PMID 30177933

Europe PMC DOI

hedged sentence

0.0006

closest p · 0.0× alpha

0.0006

boldest claim

The sentences

highly significantp = 0.0006actually significant

We showed a highly significant downregulation of nrf2 ( p = 0.0006, Figure 1A ) and nrf2 -induced genes mRNA levels in patients’ skin fibroblasts, HO-1 ( p = 0.001, Figure 1B ), GCL ( p < 0.0001, Figure 1C ), and TRX ( p < 0.0001, Figure 1D ) compared to healthy individuals.

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.