Effectiveness of fixed-dose combination therapy in hypertension: systematic review and meta-analysis.

Arch Med Sci · 2018 · PMC6111352 · PMID 30154897

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borderline significanceno p-value reported

However, they found that an increase in adherence was not statistically significant according to the pooled results of prospective trials, had borderline significance according to the pooled results of cohort studies, and was statistically significant according to the pooled results of all studies – prospective and retrospective combined [ 13 ].

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