Metabotropic Acetylcholine and Glutamate Receptors Mediate PI(4,5)P₂ Depletion and Oscillations in Hippocampal CA1 Pyramidal Neurons in situ.

We find that neither parameter shows an evident trend along the dendritic distance, suggesting that PIP 2 depletion is mostly homogenous throughout the larger dendritic compartments examined here (Pearson correlation coefficients: tubby CT -GFP amplitudes, −0.071; tubby CT -GFP time constants, 0.168;, PLCδ1-PH-GFP amplitudes, −0.209;, PLCδ1-PH-GFP time constants, −0.233).

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