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Gonadectomy in Mito-Ob mice revealed a sex-dimorphic relationship between prohibitin and sex steroids in adipose tissue biology and glucose homeostasis.

Biol Sex Differ · 2018 · PMC6114179 · PMID 30157935

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a decreasing trendno p-value reported
After gonadectomy, a decreasing trend in food intake was found in both wild-type and Mito-Ob mice (Fig. 1c, d ), implying regulation on satiety may be altered due to lack of sex steroids.

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