Computational Feasibility Analysis of Electrochemotherapy With Novel Needle-Electrode Arrays for the Treatment of Invasive Breast Ductal Carcinoma.

Furthermore, IRE cannot be avoided, mostly in the periphery of the electrodes; therefore, contribution of IRE in cell death may be significant, but it may still be tolerated for ECT. 31 Taking this into consideration, pairs of needles in the different electrode arrays were sequentially set to voltage until all combinations of unique pairs were activated, setting boundary conditions for voltage as an anode and a cathode during each simulation.

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