Hyperpolarized <sup>13</sup>C Magnetic Resonance Spectroscopy Reveals the Rate-Limiting Role of the Blood-Brain Barrier in the Cerebral Uptake and Metabolism of l-Lactate in Vivo.

Although the difference in the bicarbonate-to-lactate ratio did not quite reach the level of significance ( p = 0.45), most likely because of the low SNR, the observed trend toward increased conversion also points in the direction of an increased lactate transport rate post-ultrasound.

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