Heritability and genome-wide associations studies of cerebral blood flow in the general population.

J Cereb Blood Flow Metab · 2018 · PMC6120124 · PMID 28627999

Europe PMC DOI

hedged sentence

0.0570

closest p · 1.1× alpha

0.0570

boldest claim

The sentences

borderline significantp -value = 0.057so close (0.05 < p ≤ 0.1)

Replication We attempted replication of the two significant loci in an independent cohort and found a borderline significant and concordant signal for 6q16.1 for the flow velocity through the right carotid (rs2971609, p -value = 0.057), which is increasing in significance after meta-analysis ( p -value = 2.5 × 10 −9 ).

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