Barely Significant
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Do laws impact opioids consumption? A breakpoint analysis based on Italian sales data.

J Pain Res · 2018 · PMC6120574 · PMID 30214276

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a positive trendno p-value reported
Discussion Opioids sales in community pharmacies in Italy showed a positive trend in the period 2000–2010 ( Figure 1 ), in agreement with the trend observed in the European Union. 7 , 21 Although regulatory interventions impacted sales in both community pharmacies and hospitals, 10 the sales in community pharmacies are particularly interesting for determining the role of a less stringent regulation for opioids prescription.

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