Chitosan-Based Nanofibrous Membrane Unit with Gradient Compositional and Structural Features for Mimicking Calcified Layer in Osteochondral Matrix.

Int J Mol Sci · 2018 · PMC6121876 · PMID 30096842

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an increasing trendno p-value reported

Further, the HA content in the layered scaffold varied from the nanofibrous membrane unit to the bony layer in an increasing trend, and it is approximately consistent with the alteration of major inorganic components that are distributed in the calcified layer and the subchondral layer in the osteochondral ECM.

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