Genome organization and chromatin analysis identify transcriptional downregulation of insulin-like growth factor signaling as a hallmark of aging in developing B cells.

When we compared the expression of all genes located within regions with significantly altered compartment scores, we observed a highly significant trend towards an increase in expression of genes with an increased compartment score and vice versa (Fig. 7a , top right; p = 2.99e-40).

also in 115,300 other papers