Quantitative assessment of aberrant <i>P16<sup>INK4a</sup></i> methylation in ovarian cancer: a meta-analysis based on literature and TCGA datasets.

Cancer Manag Res · 2018 · PMC6124479 · PMID 30214298

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an increasing trendno p-value reported

Several studies reported that P16 INK4a promoter methylation was associated with an increasing trend in ovarian cancer, 20 – 23 while, other studies suggested that P16 INK4a promoter methylation was not related to the occurrence of ovarian cancer. 24 – 30 Interestingly, even the conclusions in two published meta-analyses were inconsistent.

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