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Koumine Decreases Astrocyte-Mediated Neuroinflammation and Enhances Autophagy, Contributing to Neuropathic Pain From Chronic Constriction Injury in Rats.

Front Pharmacol · 2018 · PMC6125371 · PMID 30214411

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a decreasing trendP < 0.05actually significant
In addition, although the level of Beclin-1 has no remarkable changes compared to vehicle-treated CCI and CQ-treated CCI groups, it presented a decreasing trend ( P < 0.05, Figure 6 ).

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