Barely Significant
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Population Pharmacokinetics and Cerebrospinal Fluid Penetration of Fluconazole in Adults with Cryptococcal Meningitis.

Antimicrob Agents Chemother · 2018 · PMC6125572 · PMID 29914943

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a nonsignificant trendno p-value reported
For both 2- and 10-week mortality outcomes, there was a nonsignificant trend toward reduced mortality with escalating dosage ( Fig. 5 ).

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