Osthole attenuates angiogenesis in an orthotopic mouse model of hepatocellular carcinoma via the downregulation of nuclear factor-κB and vascular endothelial growth factor.

Oncol Lett · 2018 · PMC6126190 · PMID 30214582

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a decreasing trendP<0.01actually significant

Compared with the model control group, MVD in the adjacent tissues of the osthole-treated groups exhibited a decreasing trend ( Fig. 4B ) and the expression of VEGF was also decreased (P<0.01; Fig. 4C ).

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