Biomarkers for acute diagnosis and management of stroke in neurointensive care units.

ned a major cause of disability for many years.[ 1 2 3 ] Stroke is currently the fifth leading cause of death in the United States and the third leading cause of death worldwide.[ 4 ] Although mortality caused by stroke has significantly declined over recent years, cerebrovascular diseases remain a highly significant global health burden.[ 5 6 ] The World Health Organization (WHO) defines stroke as “rapidly developing clinical signs of focal disturbance of cerebral function lasting more than 24 hours with no apparent cause other than of vascular origin.”[ 7 ] There are two main types of strokes: ischemic and hemorrhagic.

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