Patterns and severity of vascular amyloid in Alzheimer's disease associated with duplications and missense mutations in APP gene, Down syndrome and sporadic Alzheimer's disease.

Despite there being significant differences in the levels of immunostaining for plaques and CAA between the three antibodies, regression analysis showed highly significant correlations between plaque scores for each of the three antibodies ( p < 0.001 in every instance), and likewise for CAA scores ( p < 0.001 in every instance).

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For controls, this correlation failed to reach significance ( r s = 0.377, p = 0.136).

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