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Ginsenoside Rb1 does not halt osteoporotic bone loss in ovariectomized rats.

PLoS One · 2018 · PMC6136715 · PMID 30212470

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a decreasing trendno p-value reported
After ovariectomy, the four indices of blood fat in the rats increased significantly, but rats treated with GRb1 did not present a decreasing trend, except for HDL, which hinted the estrogen-deficiency model was successful but that GRb1 cannot block the deteriorating index of blood fat at the concentration we used.

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an increasing trendno p-value reported
GRb1 cannot alter the change of SOD and GSH in OVX rats, but the results of HGRb1 (high dose of GRb1 group) and LGRB1 (low dose of GRb1 group) presented an increasing trend in SOD ( S2 Fig ). 3. 4 The effect of GRb1 on bone loss in OVX rats The abundant loss of bone mineral density is one of the diagnostic criteria for osteoporosis.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.