Barely Significant
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Efficacy and safety of using topical cyclosporine A for treatment of moderate to severe dry eye disease.

Saudi J Ophthalmol · 2018 · PMC6137823 · PMID 30224886

2
hedged sentences
0.0001
closest p · 0.0× alpha
0.0001
boldest claim

The sentences

highly significantp < 0.0001actually significant
Moreover, comparing pre-intervention assessment to 12 month (during treatment) assessment yielded that the improvement in all of the assessed indices was highly significant (p < 0.0001) for Visual Acuity, BUT, and Schirmer test for both eyes.

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an increasing trendno p-value reported
1 In addition, there is an increasing trend in the frequency of patients visiting eye care facilities with dry eye symptoms. 2 The most common complaint is discomfort sensation, including a gritty and foreign body sensation, depending on the duration and severity of the dryness where the to ocular surface damage may also be present. 3 , 4 Despite being common condition, dry eye syndrome (DES) is underdiagnosed.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.