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Trends in polypharmacy over 12 years and changes in its social gradients in South Korea.

PLoS One · 2018 · PMC6143262 · PMID 30226885

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a decreasing trendno p-value reported
We observed a decreasing trend in the age-standardized prevalence of polypharmacy, from 65.8% in 2002 to 43.7% in 2013.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.