SB Driver Analysis: a Sleeping Beauty cancer driver analysis framework for identifying and prioritizing experimentally actionable oncogenes and tumor suppressors.

Nucleic Acids Res · 2018 · PMC6144815 · PMID 29846651

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hedged sentence

0.0000

closest p · 0.0× alpha

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boldest claim

The sentences

highly significantP < 10 −12actually significant

When we applied Fisher's exact test to gene sets identified by the different approaches ( Supplemental Figure S3A–C ), we always found highly significant overlap (more genes in common than expected by chance) between the SB Driver Analysis and GKC analysis methods ( P < 10 −12 ).

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