Inhaled furosemide for relief of air hunger versus sense of breathing effort: a randomized controlled trial.

However, within the FSF group, 7 of the 8 participants had substantially greater relief of AH after the second inhalation (mist 3) of furosemide compared to the first (mist 1) - a doubling of relief (mean ± SD − 10 ± 12 versus − 21 ± 13%VAS) which was highly significant (paired t-test, p = 0.002; Fig. 7 ).

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