The LAT1 inhibitor JPH203 reduces growth of thyroid carcinoma in a fully immunocompetent mouse model.

J Exp Clin Cancer Res · 2018 · PMC6150977 · PMID 30241549

Europe PMC DOI

hedged sentence

0.0571

closest p · 1.1× alpha

0.0571

boldest claim

The sentences

close to being statistically significantp = 0.0571so close (0.05 < p ≤ 0.1)

Interestingly, the surrogate transporter SNAT2 encoded by Slc38a2 , which is a sodium-dependent glutamine transporter, was 2.2-fold upregulated in BRAF V600E /PIK3CA H1047R double-mutant tumors, which was close to being statistically significant ( p = 0.0571, Fig. 4a ).

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