Barely Significant
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Impact of Zostavax Vaccination on T-Cell Accumulation and Cutaneous Gene Expression in the Skin of Older Humans After Varicella Zoster Virus Antigen-Specific Challenge.

J Infect Dis · 2018 · PMC6151076 · PMID 30247603

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highly significantno p-value reported
Furthermore, in aging individuals there is a highly significant correlation between an increased proportion of Tregs in the skin and decreased immune responses to VZV antigen challenge [ 12 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.