The overall level of LC3B-II and the ratio of LC3B-II to LC3BI were both decreased in MKN-45-DIRAS3-shRNA cells and p62 showed an increasing trend, though this was not significant, suggesting that silencing of DIRAS3 may decrease the level of autophagy in MKN-45 cells.
← all excerpts
Distinct subgroup of the Ras family member 3 (DIRAS3) expression impairs metastasis and induces autophagy of gastric cancer cells in mice.
1
—
—