Emerging Enteroviruses Causing Hand, Foot and Mouth Disease, China, 2010-2016.

Emerg Infect Dis · 2018 · PMC6154135 · PMID 30226172

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an increasing trendno p-value reported

Proportions of detection generally declined with age for other enteroviruses, whereas EV-A71 and CV-A16 showed an increasing trend with age, particularly in mild cases ( Technical Appendix Figure 2).

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a decreasing trendno p-value reported

The highest weekly proportion of EV-A71 detections among mild cases was 37.7% in 2010; a decreasing trend was observed thereafter.

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