Development of a UPLC-TQ/MS Approach for the Determination of Eleven Bioactive Components in Haizao Yuhu Decoction Plus-Minus Haizao and Gancao Drug Combination after Oral Administration in a Rat Model of Hypothyroidism.

Molecules · 2016 · PMC6155732 · PMID 28025523

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a decreasing trendno p-value reported

Although the T 1/2 of glycyrrhizinic acid showed no obvious difference in comparison with that in the GC group, its half-life showed a decreasing trend.

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