Barely Significant
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Metformin reverses early cortical network dysfunction and behavior changes in Huntington's disease.

Elife · 2018 · PMC6156080 · PMID 30179155

1
hedged sentence
0.0300
closest p · 0.6× alpha
0.0300
boldest claim

The sentences

highly significantp=0.03actually significant
In contrast to this study we here show that in vivo metformin has highly significant effects (p=0.03 to p<0.0001) already on primal changes in the very early, VFDO phases of Huntington’s disease making metformin a promising compound for the development of a therapeutic scheme that is based on early prevention of pathology development.

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