Analysis of genotype by methylation interactions through sparsity-inducing regularized regression.

BMC Proc · 2018 · PMC6157158 · PMID 30275890

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highly significantno p-value reported

However, it occasionally can be the case that variables of little marginal importance may be highly significant once interactions are included, making it desirable to consider such interactions together.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.