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Trends in fluoroquinolone resistance in Campylobacter.

Microb Genom · 2018 · PMC6159550 · PMID 30024366

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an increasing trendno p-value reported
Since the late 1980’s there has been an increasing trend in the proportion of FQ-resistant strains of members of the genus Campylobacter isolated from both clinical samples [ 11–13 ] and livestock, where FQs (particularly enrofloxacin) are frequently used to treat animals in intensive production [ 5, 7, 9, 12, 14 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.