Barely Significant
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Inflammatory mediators reduce surface PrP<sup>c</sup> on human BMVEC resulting in decreased barrier integrity.

Lab Invest · 2018 · PMC6163073 · PMID 29959417

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highly significantno p-value reported
For both mediators, this is a 40–50% reduction, that are highly significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.